Is Cream Cheese Low Histamine?

Is cream cheese low histamine? When you have histamine intolerance, what you eat matters. Histamine intolerance is a condition where the body is unable to break down histamine properly. This can lead to a build-up of histamine, which can cause various symptoms, including hives, itching, swelling, difficulty breathing, and low blood pressure.

Some foods other people enjoy can be problematic if you have histamine intolerance. But by monitoring what you eat and knowing which foods contain preformed histamine or trigger histamine release, you can avoid histamine sensitivity symptoms.

If you enjoy the smooth, creamy flavor of cream cheese on a bagel, you might wonder whether it’s safe to enjoy this combination. The simple answer is “yes,” although not all cheese is low histamine. Plus, you should take some precautions when buying commercial cream cheese to avoid aggravating histamine sensitivity and other food intolerances.

The Amount of Histamine in Cheese Varies Dramatically

Is cream cheese low histamine? Some types of cheese are off limits if you have histamine intolerance. The more aged a cheese is, the more bacteria associated with the cheese that can produce histamine. A general rule is to avoid cheeses that take a long time to ripen. (1, 2)) These include hard cheeses such as Emmental, Alpine cheese, Parmesan cheese, and even some cheddar cheese. You should also avoid Gouda cheese, as it can take a long time to ripen.

Another type of cheese to avoid is cheese made from raw milk, as raw milk cheese contains higher levels of bacteria that could produce histamine. Research suggests it’s safest to avoid all cheeses made from raw milk, cheeses that ripen quickly, and hard cheese.

But cream cheese doesn’t fall into these categories. It’s a soft, spreadable cheese made from milk and cream. The milk is first pasteurized and then cooled to form a thick mixture. This mixture is then combined with cream and an enzyme called rennet. The rennet helps thicken the mixture and gives the cream cheese its characteristic texture.

cream cheese is lower in histamine than hard cheese

About Cream Cheese and Histamine

Being a soft cheese, cream cheese is typically low in histamine and other biogenic amines. However, there’s not much data on the histamine content of processed cheese, which could contain various cheeses. For example, cream cheese may contain Emmental cheese (3), a type of cheese with a high histamine content.

Certain cheese in cream cheese could contain enough histamine to aggravate histamine intolerance symptoms. So, it’s hard to generalize and say that all cream cheese is safe to enjoy if you have histamine intolerance. Depending upon the type of cheese manufacturers use to make it, it could contain some histamine.

However, people who have histamine intolerance usually find they can tolerate cream cheese without triggering histamine sensitivity symptoms. It’s important to buy the freshest cream cheese possible and use it quickly. The longer it stays in the refrigerator, the opportunity there is for bacteria to produce histamine.

Also, avoid flavored cream cheese, since you don’t know if what they’ve added to the cheese is safe if you have histamine intolerance. Choose cream cheese that contains as few additives as possible. If you want to flavor your cream cheese, add your own herbs or spices low in histamine.

Other Biogenic Amines in Cream Cheese

When you have histamine intolerance, other biogenic amines could also trigger histamine intolerance symptoms. Histamine is only one type of biogenic amine and there are others including tyramine and tryptamine. These amines can have a variety of effects on the body, including increased heart rate, blood pressure, and anxiety. If you have histamine intolerance, you may also be sensitive to these amines.

If you have histamine intolerance, you may also be sensitive to these amines. However, this is less of a concern if you buy the freshest cream cheese and use it quickly. Biogenic amines in cream cheese usually come from storage in unsanitary conditions, or cream cheese that’s sat around for too long. (4)

Cream Cheese Is a Safer Bet Than Hard and Raw Milk Cheese

Is cream cheese high in histamine? In general, cream cheese is lower than hard cheese and raw milk cheese, but this is based on limited data that doesn’t take into account the type of cheese a manufacturer uses to make the cheese.

The lack of data on cream cheese means you should approach it with caution. Consume only a small amount at first and monitor your symptoms by keeping a food diary. That’s the best approach for any food that you eat that isn’t clearly low in histamine.

Here’s the good news! Most people with histamine intolerance can enjoy cream cheese in moderate quantities, without triggering histamine intolerance symptoms. But each person with histamine intolerance is a little different, see how you respond. Hopefully, you can enjoy it moderation! Find out about other low-histamine dairy foods.

keep a food diary if you consume cream cheese


  1. Fonberg-Broczek M, Sawilska-Rautenstrauch D. Zawartość histaminy i tyraminy w serach dojrzewajacych pobranych z obrotu [Level of histamine and tyramine in ripening cheeses]. Rocz Panstw Zakl Hig. 1995;46(3):243-6. Polish. PMID: 8552964.
  2. Madejska A, Michalski M, Pawul-Gruba M, Osek J. Histamine Content in Rennet Ripening Cheeses During Storage at Different Temperatures and Times. J Vet Res. 2018 Mar 30;62(1):65-69. doi: 10.1515/jvetres-2018-0009. PMID: 29978129; PMCID: PMC5957463.
  3. “Effect of post-ripening processing on the histamine and histamine ….” 01 Dec. 2009,
  4. “Occurrence of Toxic Biogenic Amines in Various Types of Soft and Hard ….” 13 Jul. 2022,

I'm Dr. Kristie Leong M.D. M.S. I graduated from Virginia Commonwealth University and have a deep interest and passion for histamine intolerance. My journey includes a comprehensive Kindle ebook on Histamine Intolerance and its dietary management.With a Masters in Clinical Pathology, my knowledge of immunology adds a robust scientific foundation to my expertise. I wholeheartedly believe in the power of lifestyle and prevention in healthcare. Let's work together to manage histamine intolerance through practical dietary and lifestyle choices. :-)